Mechanisms of action and key actives
Tricocure targets three decisive drivers of progressive hair loss—androgen (DHT)‑related miniaturization, insufficient microcirculation, and structural weakening within the follicular matrix.
The formulation combines documented DHT modulators (e.g., Biochanin A, beta‑sitosterol and Serenoa repens) with Kopexil, which relaxes the perifollicular collagen “sheath” and counters shaft‑diameter loss.
In parallel, CG‑VEGF stimulation and niacin provide vasodilation and pro‑angiogenic support, increasing nutrient delivery to the anagen hair follicle.
Acetyl Tetrapeptide‑3 targets dermal papilla/ECM remodelling for stronger anchoring, while biotin and B‑vitamins support keratin synthesis and cuticle integrity.
Results in clinical practice
- Reduced shedding by dampening 5‑alpha‑reductase/androgen signalling and interrupting the miniaturization cascade.
- Improved perfusion in perifollicular tissue → more stable anagen and better nutrient uptake.
- Visibly stronger shafts via ECM/peptide stimulation and keratin support.
- Topical protocol: 3 ml twice daily on dry scalp with a precision applicator. Consider interval‑based microneedling/PRP; avoid concurrent irritants.
- Patient profiles: Early to moderate androgenetic hair loss (men/women), post‑stress/post‑partum telogen worsening, and maintenance after stimulating courses.
- Expectation setting: Less shedding in 3–6 weeks; fuller appearance typically in 8–12 weeks with consistent compliance. Maintain thereafter to stabilize results.
Growth factor (CG‑VEGF)
- Kopexil — supports angiogenesis and nutrient supply at the follicle base, actively stimulating hair growth.
- Saw palmetto extract (Serenoa repens) — counters hormonal signalling and reduces follicular exposure to DHT.
- Beta‑sitosterol — a natural plant extract with antiandrogen activity; targets hormones that contribute to androgenetic alopecia.
- Capixyl — a combination of Biochanin A (inhibits 5‑alpha‑reductase I/II) and Acetyl Tetrapeptide‑3 (stimulates tissue remodelling) to enlarge the follicle for better anchoring and vitality.
Vitamins and botanical modulators
- Biotin (B7): supports keratin synthesis and new hair formation.
- Niacin (B3): vasodilation and increased scalp blood flow.
- Pyridoxine (B6): contributes to melanin formation and may reduce hair loss.
- Pantothenic acid (B5): associated with less greying and reduced shedding.
- American ginseng: increases stimulation and improves circulation.